Dr. Amnon Buxboim
We are interested in how the interactions between cells and their physical environment direct cell-fate decision making. The biological systems that we study are (by increasing length scale and complexity):
The Cell Nucleus – where genes are regulated
Stem Cell Differentiation and Epigenetic Reprogramming
Pre-Implantation Embryogenic Development
Muscle functions in Myotonic Dystrophy
We design state-of-the-art experimental systems to control 2D/3D matrix elasticity, applied stretch and contraction forces, and pressure to mimic the physiological stimuli that cells are subjected to. Our lab is highly interdisciplinary and integrates Cell & Molecular Biology with Physics, Bioengineering and Computer Science.